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Pharmacokinetics and metabolism in drug design by Dennis A. Smith

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Published by Wiley-VCH in Weinheim, New York .
Written in English

Subjects:

  • Pharmacokinetics.,
  • Drugs -- Metabolism.,
  • Drugs -- Design.

Book details:

Edition Notes

Includes bibliographical references and index.

Statementby Dennis A. Smith, Han van de Waterbeemd, and Don K. Walker.
SeriesMethods and principles in medicinal chemistry ;, v. 13
ContributionsWaterbeemd, Han van de., Walker, Don K.
Classifications
LC ClassificationsRM301.5 .S65 2001
The Physical Object
Paginationxi, 149 p. :
Number of Pages149
ID Numbers
Open LibraryOL3344915M
ISBN 103527301976
LC Control Number2004351428
OCLC/WorldCa48416981

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Pharmacokinetics and Metabolism in Drug Design, 3rd Edition. Read an Excerpt Excerpt 1: the book relates physicochemistry and chemical structure to pharmacokinetic properties and ultimately drug efficacy and safety. particularly where drug metabolism impacts on the design of more efficacious and safer : Dennis A. Smith. Pharmacokinetics and Metabolism in Drug Design, 2nd edition (Methods and Principles in Medicinal Chemistry) Dennis A. Smith, Han van de Waterbeemd, Don K. Walker In this new edition of a bestseller, all the contents have been updated and new material has been added, especially in the areas of toxicity testing and high throughput analysis. Drug Metabolism and Pharmacokinetics Quick Guide is intended for broad readership of those interested in the discipline of drug metabolism and pharmacokinetics who work in drug discovery coming from the various disciplines, a background such as of medicinal chemistry, pharmacology, drug metabolism and pharmacokinetics, bioanalysis, clinical sciences, biochemistry, pharmaceutics or . PHARMACOKINETICS AND METABOLISM IN chapter of this book dealing with drug design, we return to this topic and describe further examples of the incorporation of metabolism and PK data into various strategies for increasing the therapeutic indices of new candidate drugs.

Pharmacokinetics and drug metabolism in the elderly Aging involves progressive impairments in the functional reserve of multiple organs, which might also affect drug metabolism and pharmacokinetics. In addition, the elderly population will develop multiple diseases and, consequently, often has to take several drugs. Department of Drug Metabolism Sandwich, Kent CT13 9NJ UK @ & All books published by Wiley-VCH are carefully produced. Nevertheless, authors, editors, and publisher do not warrant the information contained in these books, including this book, to be free of errors. Readers are advised to keep in mind that.   Buy Pharmacokinetics and Metabolism in Drug Design (Methods and Principles in Medicinal Chemistry) 3rd by Smith, Dennis A., Allerton, Charlotte, Kalgutkar, Amit S., Waterbeemd, Han van de, Walker, Don K., Mannhold, Raimund, Kubinyi, Hugo, Folkers, Gerd (ISBN: ) from Amazon's Book Store. Everyday low prices and free delivery on eligible s: 2. Pharmacokinetics and Metabolism in Drug Design / Edition 3 available in Hardcover, NOOK Book. the book relates physicochemistry and chemical structure to pharmacokinetic properties and ultimately drug efficacy and safety. Product Details; particularly where drug metabolism impacts on the design of more efficacious and safer : $