Includes bibliographical references and index.
|Statement||by Dennis A. Smith, Han van de Waterbeemd, and Don K. Walker.|
|Series||Methods and principles in medicinal chemistry ;, v. 13|
|Contributions||Waterbeemd, Han van de., Walker, Don K.|
|LC Classifications||RM301.5 .S65 2001|
|The Physical Object|
|Pagination||xi, 149 p. :|
|Number of Pages||149|
|LC Control Number||2004351428|
Pharmacokinetics and Metabolism in Drug Design (Methods and Principles in Medicinal Chemistry Book 51) 3rd Edition, Kindle Edition by Dennis A. Smith (Editor), Charlotte Allerton (Editor), Amit S. Kalgutkar (Editor), Han van de Waterbeemd (Editor), Don K. Walker (Editor) & 2 more Format: Kindle Edition/5(2). Thus, this book is aimed at all those dealing professionally with the development and application of pharmaceutical substances. Furthermore, the readily comprehensible style of writing makes it equally suitable for students of pharmacy and related subjects, who feel that pharmacokinetics is covered too briefly in the standard textbooks. focuses on the impact of pharmacokinetics and metabolism in Drug Design. Phar-macokinetics is the study of the kinetics of absorption, distribution, metabolism, and excretion of drugs and their pharmacologic, therapeutic, or toxic response in animals and man. In the last 10 years drug discovery has changed rapidly. Combinatorial chemistry. Pharmacokinetics and Metabolism in Drug Design | Dennis A. Smith, Han van de Waterbeemd, Don K. Walker, Raimund Mannhold, Hugo Kubinyi, Hendrik Timmerman | download | B–OK. Download books for free. Find books.
Pharmacokinetics and Metabolism in Drug Design, 3rd Edition. Read an Excerpt Excerpt 1: the book relates physicochemistry and chemical structure to pharmacokinetic properties and ultimately drug efficacy and safety. particularly where drug metabolism impacts on the design of more efficacious and safer : Dennis A. Smith. Pharmacokinetics and Metabolism in Drug Design, 2nd edition (Methods and Principles in Medicinal Chemistry) Dennis A. Smith, Han van de Waterbeemd, Don K. Walker In this new edition of a bestseller, all the contents have been updated and new material has been added, especially in the areas of toxicity testing and high throughput analysis. Drug Metabolism and Pharmacokinetics Quick Guide is intended for broad readership of those interested in the discipline of drug metabolism and pharmacokinetics who work in drug discovery coming from the various disciplines, a background such as of medicinal chemistry, pharmacology, drug metabolism and pharmacokinetics, bioanalysis, clinical sciences, biochemistry, pharmaceutics or . PHARMACOKINETICS AND METABOLISM IN chapter of this book dealing with drug design, we return to this topic and describe further examples of the incorporation of metabolism and PK data into various strategies for increasing the therapeutic indices of new candidate drugs.
Pharmacokinetics and drug metabolism in the elderly Aging involves progressive impairments in the functional reserve of multiple organs, which might also affect drug metabolism and pharmacokinetics. In addition, the elderly population will develop multiple diseases and, consequently, often has to take several drugs. Department of Drug Metabolism Sandwich, Kent CT13 9NJ UK @ & All books published by Wiley-VCH are carefully produced. Nevertheless, authors, editors, and publisher do not warrant the information contained in these books, including this book, to be free of errors. Readers are advised to keep in mind that. Buy Pharmacokinetics and Metabolism in Drug Design (Methods and Principles in Medicinal Chemistry) 3rd by Smith, Dennis A., Allerton, Charlotte, Kalgutkar, Amit S., Waterbeemd, Han van de, Walker, Don K., Mannhold, Raimund, Kubinyi, Hugo, Folkers, Gerd (ISBN: ) from Amazon's Book Store. Everyday low prices and free delivery on eligible s: 2. Pharmacokinetics and Metabolism in Drug Design / Edition 3 available in Hardcover, NOOK Book. the book relates physicochemistry and chemical structure to pharmacokinetic properties and ultimately drug efficacy and safety. Product Details; particularly where drug metabolism impacts on the design of more efficacious and safer : $